First seen in the episode Shen Yi Bu, some Shen Gong Wu can be used in unison and result in completely different effects, essentially becoming a new Shen Gong Wu. The following combinations are those that have been used within the series.

Raimundo first demonstrated the capabilities of Shen Gong Wu combinations by using the Eye of Dashi and the Sword of the Storm against Tubbimura in the first Shen Yi Bu Dare. This combination allows the user to fly around at lightning speed, causing all forms of wind related mayhem.

When the Xiaolin Warriors reached Apprentice level, they were taught that many Shen Gong Wu, when coupled with the name of their Element, gain new powers.

When Omi uses the Orb of Tornami with his Water Element, the Orb of Tornami can freeze objects, instead of merely producing an endless supply of liquid water (The way this combination was activated was later changed to "Orb of Tornami-Ice" for unknown reasons).

When Kimiko uses the Star Hanabi or the Eye of Dashi with her Fire Element, the Shen Gong Wu can create fire instead of fireworks or lightning.

When Raimundo uses the Sword of the Storm or the Eye of Dashi with his Wind Element, both Shen Gong Wu can conjure up strong winds, and the Eye of Dashi can create storms.

When Clay uses the Third-Arm Sash with his Earth Element, it can turn into stone. He can also use the Fist of Tebigong with the Earth Element to create fissures in the ground.

It is assumed that other Shen Gong Wu gain these powers as well.

The Mosaic Scale held the imprisoned spirit of mischief, Sibini, and the Monarch Wings, the Mosaic Scale's sister Shen Gong Wu, would imbue Sibini with the ultimate strength and power of mayhem. When Sibini was freed from a broken Mosaic Scale, he took over Clay's body in preparation for the Monarch Wings' activation. Without the Monarch Wings, Sibini cannot exist very long on his own.

Before Sibini could attain ultimate power with the Mosaic Scale and the Monarch Wings, he was trapped within them by Kimiko using the Eye of Dashi and her Fire Element.

When the Heart of Jong, the Helmet of Jong, the Two-Ton Tunic, the Jetbootsu, the Fist of Tebigong, the Third-Arm Sash, the Shroud of Shadows, and the Eye of Dashi are brought together, they create Mala Mala Jong, an ancient evil demonic warrior. The person to defeat Mala Mala Jong was Omi, using the Serpent's Tail and the retrieved Golden Tiger Claws from the center of the earth from the molten lava. He then took the Heart of Jong from Mala Mala Jong's chest. The Heart of Jong gives life to the lifeless, and as long as Mala Mala Jong has the Heart of Jong within itself, it can use all of the other Shen Gong Wu as if it were a human. Mala Mala Jong can either be brought into existance by others forming him, or by the mystical alignment of the planets.

It is quite possible that all Shen Gong Wu could combine to become an unstoppable version of Mala Mala Jong.

The Reversing Mirror is a Shen Gong Wu which can be used with any other Shen Gong Wu to perform the opposite of what it would normally do. The example given by the Mystical Scroll of the Shen Gong Wu shows that the Two-Ton Tunic would become as light as a feather. When the Reversing Mirror is used by a single person, and that person is about to be attacked by someone else Shen Gong Wu, the Shen Gong Wu backfires on its user. An example of this would be when Omi used the Fist of Tebigong on Jack Spicer, who then used the Reversing Mirror, resulting in Omi hitting himself with the Fist of Tebigong. This, however, is not a combination of the two Shen Gong Wu, but is merely the effect of the Reversing Mirror being used by itself.

Below are various Shen Gong Wu that have been used in conjunction with the Reversing Mirror and have had their effects reversed.

• Changing Chopsticks: The Reversing Mirror and the Changing Chopsticks make objects or people larger instead of smaller. In order to undo the change, the Reversing Mirror and Changing Chopsticks must both be used again, or the change is irreversible. If one tries to use just the Changing Chopsticks, they will become progressively smaller than their original size
  
• Crystal Glasses: When the Crystal Glasses look into the reflection of the Reversing Mirror, the user looks into a false or "opposite" future, than what will happen.
  
• Gills Of Hamachi: When the Reversing Mirror and Gills of Hamachi are used at the same time, they can cause someone to lose the ability to breathe underwater and swim.
  
• Fountain of Hui & Eagle Scope: The user of these Shen Gong Wu sees the opposite information than what they desire. For example, instead of discovering the way to destroy evil, they mistakenly discover the way to destroy good.

When the Serpent's Tail is used in conjunction with the Reversing Mirror, it can makes non-corporeal (ghostly) entities solid. This dangerous combination is capable of returning Wuya, the Ancient Heylin Witch, to her physical form, since she was reduced to a ghost after being trapped in a magical puzzle box. This can bring Wuya back to her physical form with or without her full magical powers, if the user knows how.

When Mala Mala Jong receives the Ring of the Nine Dragons, it divides itself into the Fearsome Four, four separate Mala Mala Jongs that have slightly altered parts. Apparently, according to the Ancient Scroll, the appearance of the Fearsome Four symbolizes the end of the world. The only way to control the Mala Mala Jongs is to use the Emperor Scorpion, a Shen Gong Wu that can control other Shen Gong Wu.

When combined, the Ying Yo-Yo and the Yang Yo-Yo become the Ying-Yang Yo-Yo, allowing the user to travel into the Ying-Yang World and leave without having either their good or evil chi trapped within the other dimension. If either Shen Gong Wu were to be used alone, one form of chi would be lost depending on whether or not the user was good or evil. The Ying-Ying Bird (Hannibal Roy Bean's messenger) is apparently immune to the magics of the Ying-Yang World and remains evil when it leaves.

Although used only twice (by Raimundo and Omi), when the user activates a Shen Gong Wu and then calls out his or her Wudai Element Attack, he or she can use a combined impulse attack.

When Raimundo used the Cannon Blaster and then called out, "Wudai Star-Wind," he became a charged thunder ball.

When Omi used the Orb of Tornami and then called out, "Wudai Neptune-Ice," he was able to freeze anything in sight while using it to boost himself upwards.